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Rice Functional Genomics and Agrobiotechnology


     The ChuLab mainly focuses on functional genomics and Agrobiotechnology by the use of rice as a model system. Besides tremendous efforts on germplasm collection, generation and screening of mutant population in last decades, the germplasms and mutants involved in agronomically important traits related to the plant architecture, source supply, and sink capacity, etc have been characterized, to dissect the molecular basis for rice yield improvement. Besides functional characterization of rice genes, we also make significant effort on Agrobiotechnology by using the knowledge, resources and tools obtained from our studies and combine approaches of genetics, molecular technologies, such as marker-assisted selection to improve complex agronomic traits. We are particularly interested in leaf senescence, grain size, nutrient use efficiency, the key agronomic traits in rice production. 

Selected Publications
 
Wang H, Xu X, Vieira FG, Xiao Y, Li Z, Wang J, Nielsen R, and Chu C (2016) The power of inbreeding: NGS based GWAS of rice reveals convergent evolution during rice domestication. Mol. Plant 9(7):975-985
Cover Story. Featured in Molecular Plant by Xuehui Huang (2016) “From Genetic Mapping to Molecular Breeding: Genomics Have Paved the Highway”. 9(7):959-960.
 
Gao S, Fang J, Xu F, Wang W, Chu C (2016) Rice HOX12 regulates panicle exsertion by directly modulating the expression of ELONGATED UPPERMOST INTERNODE1. Plant Cell 28(3): 680-695.
Highlighted in Science Daily on April 1, 2016 by Jennifer Lockhart: Feeding the world: Uncovering a key regulator of flower head development in rice.
 
Che R, Tong H, Shi B, Liu Y, Fang S, Liu D, Xiao Y, Hu B, Liu L, Wang H, Zhao M, Chu C (2015) Control of grain size and rice yield by GL2-mediated brassinosteroid responses. Nature Plants 2: 15195.
Featured with News and Views in Nature Plants by Hirokazu Tsukaya: Yield increase: GRFs provide the key. 2: 15210.
 
Liu L^, Tong H^, Xiao Y, Che R, Xu F, Hu B, Liang C, Chu J, Li J*, Chu C* (2015) Activation of Big Grain1 significantly improves grain size by regulating auxin transport in rice. Proc. Natl. Acad. Sci. USA 112(35): 11102-11107 (*Corresponding authors).
 
Chu C (2015) A new era for crop improvement – From model-guided rationale design to practical engineering. Mol. Plant 8(9): 1299-1301.

Hu B, Wang W, Ou S, Tang J, Li H, Che R, Zhang Z, Chai X, Wang H, Wang Y, Liang C, Liu L, Piao Z, Deng Q, Deng K, Xu C, Liang Y, Zhang L, Li L, Chu C (2015) Variation in NRT1.1B contributes to nitrate-use divergence between rice subspecies. Nature Genet. 47(7): 834-838.
Featured with News and Views in Nature Plants by Chao DY & Lin HX (2015) Nitrogen-use efficiency: Transport solution in rice variations. 1: 15096.

Tong H, Xiao Y, Liu D, Gao S, Liu L, Yin Y, Jin Y, Qian Q, Chu C (2014) Brassinosteroid regulates cell elongation by modulating gibberellin metabolism in rice. Plant Cell 26(11): 4376-4393.

Liang C, Wang Y, Zhu Y, Tang J, Hu B, Liu L, Ou S, Wu H, Sun X, Chu J, and Chu C (2014) OsNAP connects absisic acid and leaf senescence by fine tuning absisic acid biosynthesis and directly targeting senescence-associated genes in rice. Proc. Natl. Acad. Sci. USA 111(27): 10013-10018.

Sun C, Fang J, Zhao T, Xu B, Zhang F, Liu L, Tang J, Zhang G, Deng X, Chen F, Qian Q, Cao X, Chu C (2012) The histone methyltransferase SDG724 mediates H3K36me2/3 deposition at MADS50 and RFT1, and promotes flowering in rice. Plant Cell 24(8): 3235-3247.
 
Tong H, Liu L, Jin Y, Du L, Yin Y, Qian Q, Zhu L, Chu C (2012) DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice. Plant Cell 24(6): 2562–2577.
 
Wu HJ, Zhang Z, Wang JY, Oh DH, Dassanayake M, Liu B, Huang Q, Sun HX, Xia R, Wu Y, Wang Y, Yang Z, Liu Y, Zhang W, Zhang H, Chu J, Yan C, Fang S, Zhang J, Wang Y, Zhang F, Wang G, Lee SY, Cheeseman JM, Yang B, Li B, Min J, Yang L, Wang J*, Chu C*, Chen SY*, Bohnert HJ*, Zhu J-K*, Wang XJ*, Xie Q* (2012) Insights into salt tolerance from the genome of Thellungiella salsuginea. Proc. Natl. Acad. Sci. USA 109(30): 12219-12224 (*Corresponding author).
 
Li C, Wang Y, Liu L, Hu Y, Zhang F, Sodmergen, Wang G, Schläppi MR, Chu C (2011) A rice plastidial nucleotide sugar epimerase is involved in galactolipid biosynthesis and improves photosynthetic efficiency. PLoS Genet. 7(7): e1002196.  

Ding Y, Wang X, Su L, Zhai J, Cao S, Zhang D, Liu C, Bi Y, Qian Q, Cheng Z, Chu C*, Cao X* (2007) SDG714, a histone H3K9 methyltransferase, is involved in Tos17 DNA methylation and transposition in rice. Plant Cell 19(1): 9-22 (*Corresponding author).